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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPHA5
All Species:
14.24
Human Site:
Y982
Identified Species:
34.81
UniProt:
P54756
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54756
NP_004430.4
1037
114803
Y982
E
A
I
K
M
G
R
Y
T
E
I
F
M
E
N
Chimpanzee
Pan troglodytes
XP_001165182
1037
114815
Y982
E
A
I
K
M
G
R
Y
T
E
I
F
M
E
N
Rhesus Macaque
Macaca mulatta
XP_001110034
1038
114840
Y983
E
A
I
K
M
G
R
Y
T
E
I
F
M
E
N
Dog
Lupus familis
XP_545052
972
108820
E925
K
E
I
F
T
G
V
E
Y
S
S
C
D
T
I
Cat
Felis silvestris
Mouse
Mus musculus
P29319
983
109937
E936
K
E
I
F
T
G
V
E
Y
S
S
C
D
T
I
Rat
Rattus norvegicus
P54757
1005
110989
L958
S
S
R
V
S
T
L
L
A
E
H
G
S
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510807
979
108960
G932
T
E
I
F
M
E
N
G
Y
S
S
M
D
A
V
Chicken
Gallus gallus
P54755
1013
112227
Y958
E
A
I
K
M
G
R
Y
T
E
I
F
M
E
N
Frog
Xenopus laevis
Q91845
986
109822
S939
F
T
A
A
G
Y
T
S
L
E
A
V
V
H
V
Zebra Danio
Brachydanio rerio
O13146
981
109636
A934
Y
K
E
H
F
S
S
A
G
Y
V
T
L
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.2
63.8
N.A.
64
92.8
N.A.
90
90.6
62.5
60.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.9
99.6
78.6
N.A.
78.6
94.1
N.A.
92.3
93.9
75.4
73.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
13.3
N.A.
13.3
6.6
N.A.
13.3
100
6.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
20
N.A.
20
13.3
N.A.
13.3
100
13.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
40
10
10
0
0
0
10
10
0
10
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
20
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
30
10
0
% D
% Glu:
40
30
10
0
0
10
0
20
0
60
0
0
0
40
0
% E
% Phe:
10
0
0
30
10
0
0
0
0
0
0
40
0
0
0
% F
% Gly:
0
0
0
0
10
60
0
10
10
0
0
10
0
0
10
% G
% His:
0
0
0
10
0
0
0
0
0
0
10
0
0
10
0
% H
% Ile:
0
0
70
0
0
0
0
0
0
0
40
0
0
0
20
% I
% Lys:
20
10
0
40
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
10
10
10
0
0
0
10
10
0
% L
% Met:
0
0
0
0
50
0
0
0
0
0
0
10
40
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
40
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
10
0
0
0
40
0
0
0
0
0
0
0
0
% R
% Ser:
10
10
0
0
10
10
10
10
0
30
30
0
10
0
10
% S
% Thr:
10
10
0
0
20
10
10
0
40
0
0
10
0
20
0
% T
% Val:
0
0
0
10
0
0
20
0
0
0
10
10
10
0
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
10
0
40
30
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _